How I can update the ReaderAccess settings?

I searching the method to update the ReaderAccess settings in an existing database ?

Subject: How I can update the ReaderAccess settings ?

Can you provide a bit more information?

Is this a single database? Is this one or several people that need to be added, and does the list change frequently? Why do you need to automate it?

Is opening the database to the Access Control List not available to you?