I’ve never been able to fix this before short of deleting the users and re-installing them from scratch.
I finally got one to repair by
1 change the shortname and front of the email address to be the same. I first changed them both to “zzz” and then back to the proper name to make sure it was written.
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I replaced the database design with Domino Web Mail and then Make to a regular mail template.
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I used the updall -T $user command mentioned in many of the other posts.
4 did a tell router quit
5 deleted all the *.box files
6 restarted the router
Sent some test mail and it worked. I have my doubts that this will work everytime, for myself or anyone else, but hopefully it helps some of the people some of the time.