Slow Client Opens (6.x/7.x) - 8.5.1 FP2 Server

We have an 8.5.1 FP2 mail server and clients (mixed 6.5x-8.5x) report intermittent issues with performance… like 2 minute opens, etc. Some of our routine server tasks seem to take forever to complete. The server is running on VMWare ESX 4.1. Any ideas?

Subject: Solution (Slow Opens)

Fixed… apply IF1!