Domino and IIS problem with multiple Domino Servers

I have an iis server running with two web instances. eg. server1.xyz.com and server2.yz.com. I want to connect over the was_plugin to two different dominoservers.

From server1.yz.com to domino1.xyz.com and from server2.xyz.com to domino2.xyz.com.

Is this possible ? and if it is possible how do i have to configure my plugin-cfg.xml file.

Regards Dieter