Document Management (non-Lotus) & MAPI requirement

Does anyone remember the notes.ini entry used to support MAPI requests on the Domino server (or if even required anymore). Our non-Lotus document management program is attempting to make MAPI calls to Domino without success. I think it’s referencing a DLL like nmailman.dll. Anyone out there had a non-Lotus app that needed to use MAPI against Domino? Thanks…