Attached Visio

I am having trouble with users attempting to open Visio files attached to Notes documents in the web browser. I added the MIME association to the http.cnf file, and have confirmed that the http header is recognizing it as the correct file type. However, after the browser brings up the save/open dialogue, it won’t do anything if open is selected (it works fine with save). I have tried changing my local file options to open the file in a new window, and leaving it in the same window to no avail. I have had my coworkers testing it, and, they get the same results that I do (with either Visio 2000 or 2003 and different versions of the Visio viewer). Has anyone run into anything similar that can shed some light as to what is going on?